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Evaluation of two short standardized regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicenter, randomized, non-inferiority trial

In STREAM stage 2, this study compared two bedaquiline-containing regimens with the 9-month STREAM stage 1 regimen. Both bedaquiline-containing regimens, a 9-month oral regimen and a 6-month regimen with 8 weeks of second-line injectable, had superior efficacy compared with a 9-month injectable-containing regimen, with fewer cases of hearing loss.

Published: November 8, 2022

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